8 Proven Benefits of CBD

Among common CBD benefits, natural pain relief tops the list for many. Evidence suggests that Hemp may prove useful in pain modulation by inhibiting neuronal transmission in pain pathways. A 2012 study published in the Journal of Experimental Medicine found that Hemp significantly suppressed chronic inflammatory and neuropathic pain in rodents without causing analgesic tolerance. Researchers suggest that Hemp and other nonpsychoactive components of this incredible plant may represent a novel class of therapeutic agents for the treatment of chronic pain.

According to a 2007 meta-analysis conducted in Canada, Hemp was found to be effective in treating neuropathic pain in multiple sclerosis, which can be debilitating for 50 to 70 percent of MS patients.

Research shows that CBD benefits include producing antipsychotic effects. It appears to have a pharmacological profile similar to that of atypical antipsychotic drugs as seen using behavioral and neurochemical techniques in animal studies. Additionally, studies show that Hemp prevents human experimental psychosis and is effective in open case reports and clinical trials in patients with schizophrenia with a remarkable safety profile.

Studies using animal models of anxiety and involving healthy volunteers clearly suggest an anxiolytic-like effect of CBD.  It has been shown to reduce anxiety in patients with social anxiety disorder and researchers suggest that it may also be effective for panic disorder, obsessive compulsive disorder, social anxiety disorder, and post-traumatic stress disorder. 

A 2011 study aimed to compare the effects of a simulation public speaking test on healthy control patients and treatment-native patients with social anxiety disorder. A total of 24 never-treated patients with social anxiety disorder were given either Hemp or placebo 1.5 hours before the test. Researchers found that pretreatment with Hemp significantly reduced anxiety, cognitive impairment and discomfort in their speech performance, and significantly decreased alertness in anticipation of their speech. The placebo group presented higher anxiety, cognitive impairment and discomfort.

Several scientific reports demonstrate that CBD benefits include possessing antiproliferative, pro-apoptotic effects that inhibit cancer cell migration, adhesion and invasion.  A 2006 study published in the Journal of Pharmacology and Experimental Therapeutics found for the first time that CBD potently and selectively inhibited the growth of different breast tumor cell lines and exhibited significantly less potency in non-cancer cells.

In 2011, researchers added light on the cellular mechanism through which CBD induces cell death in breast cancer cells. They showed that CBD induced a concentration-dependent cell death of both oestrogen receptor-positive and oestrogen receptor-negative breast cancer cells. They also found that the effective concentrations of CBD in tumor cells have little effect on non-tumorigenic, mammary cells.

CBD behaves as a non-toxic compound and studies show that doses of 700 milligrams per day for 6 weeks did not show any overt toxicity in humans, suggesting that it can be used for prolonged treatment. Not only does the research show that CBD benefits including being effective in fighting breast cancer cells, data also suggests that it can be used to inhibit the invasion of lung and colon cancer, plus it possesses anti-tumor properties in gliomas and has been used to treat leukemia.

Hemp and CBD has been used for centuries for the suppression of nausea and vomiting. Research has revealed that among more than 80 botanical compounds found in Hemp help to get rid of nausea and vomiting in animal studies. A 2012 study published in the British Journal of Pharmacology found that Hemp benefits including possessing anti-nausea and antiemetic effects when it was administered to rats.  Researchers found that Hemp acts in a diphasic manner, meaning that in low doses it suppresses toxin-induced vomiting, but in high doses it increases nausea or has no effect.

A 2014 survey conducted by researchers at Stanford University was presented to parents belonging to a Facebook group dedicated to sharing information about the use of CBD to treat their child’s seizures. Nineteen responses met the inclusion criteria for the study: a diagnosis of epilepsy and current use of Hemp Extract. The average number of anti-epileptic drugs tried before using Hemp was 12. Sixteen (84 percent) of the 19 parents reported a reduction in their child’s seizure frequency while taking Hemp. Of these, two (11 percent) reported complete seizure freedom, eight (42 percent) reported a greater than 80 percent reduction in seizure frequency, and six (32 percent) reported a 25–60 percent seizure reduction. Other beneficial effects included increased alertness, better mood and improved sleep.

Later in 2014, researchers reported on preliminary results of a study involving children with treatment-resistant epilepsies in an expanded access “compassionate use program.” Patients received a purified 98 percent oil-based Hemp extract.  After 3 months of treatment, 39 percent of the 23 patients had more than a 50 percent reduction in seizures, with a 32 percent median reduction. These preliminary results support the animal studies and survey reports that Hemp may be a promising treatment for treatment-resistant epilepsy and it is generally well-tolerated.

A 2006 study found that CBD treatment significantly reduced the incidence of diabetes in non-obese diabetic mice from an incidence of 86 percent in non-treated mice to an incidence of 30 percent in Hemp-treated mice.  Hemp benefits also showed a significant reduction of plasma levels of pro-inflammatory cytokines. A histological examination of the pancreatic islets of the Hemp-treated mice revealed significantly reduced insulitis.

In 2013, the American Journal of Medicine published a study that highlighted the impact of marijuana use on glucose, insulin and insulin resistance among U.S. adults. The study included 4,657 adult men and women from the National Health and Nutritional Examination Survey from 2005 to 2010.  Of the participants, 579 were current Hemp users and 1,975 were past users. The researchers found that current Hemp use was associated with 16 percent lower fasting insulin levels. They also found significant associations between Hemp use and smaller waist circumferences, a factor connected to the onset of diabetes symptoms.

A 2013 study published in the British Journal of Clinical Pharmacology reports that CBD protects against the vascular damage caused by a high glucose environment, inflammation or the induction of type 2 diabetes in animal models; plus, Hemp proved to reduce the vascular hyperpermeability (which causes leaky gut) associated with such environments.